|
KMID : 0895820090190010011
|
|
Journal of Oriental Rehabilitation Medicine
2009 Volume.19 No. 1 p.11 ~ p.21
|
|
|
Muscle Type Change and Vascularization Effect of Semen Persicae in MCAo rats
|
|
Kwon Hyeok-Joon
Kim Ho-Jun
Soh Kab-Seog
Lee Myeong-Jong
|
|
|
Abstract
|
|
|
Objectives :This study was performed to investigate the effects of Semen Persicae(SP) on muscle type change and vascularization effect by measuring expression of Myosin heavy chain (MHC) and Vascular endothelial growth factor (VEGF) protein in the Middle cerebral artery occlusion(MCAo) rats.
Methods :The middle cerebral artery was occluded, SP extraction was administrated for 4 days. The effects of SP on muscle type change and vascularization were measured.
Results :1. VEGF protein expressions in the Semen Persicae oral administration group of MCAo group were increased compared to the control group. 2. There were no significant difference between the Semen Persicae oral administration of MCAo group and the control group in MHC isoform (Type I, Type IIa) expression change.
Conclusion :The present study demonstrates the effect of Semen Persicae in the vascularizing after ischemia, but has no significant effect in musle type change and the improvement of musle atrophy.
|
|
|
KEYWORD
|
|
|
Middle cerebral artery occlusion(MCAo), Semen Persicae, Myosin heavy chain(MHC), Vascular endothelial growth factor(VEGF)
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|